Mahasneh Adel M
Department of Biological Sciences, University of Jordan, Amman, Jordan.
Phytother Res. 2002 Dec;16(8):751-3. doi: 10.1002/ptr.1037.
Aqueous, ethanol and butanol crude extracts of the aerial parts of ten plants exhibited variable degrees of antimicrobial activity against four bacterial and two fungal species. Aqueous extracts had low antimicrobial activity against E.coli, P.aeruginosa, B. cerreus, S.aureus, C.albicans and A.flavus. Avicennia marina (AM) aqueous extract exhibited a moderate antifungal activity. Ethanol and butanol crude extracts exhibited an improved antimicrobial activity. However, butanol exhibited a superior antimicrobial activity compared with aqueous and ethanol crudes. Compared with the standard antibiotics tested the butanol extract had the highest activity. Butanol extracts at 2000 microg/disc of AM, Lotus halophilus (LA), Pulicaria gnaphaloides (PG) and Capparis spinosa (CS) had a very good antibacterial activity against both gram-positive and -negative bacteria as well as moderate to good antifungal activity against C. albicans and A. flavus. Medicago laciniata (ML), Limonium axillare (LA) and (PG) butanol crude extract compared with standard chloramphenicol, tetracycline and nalidixic acid exhibited a superior antifungal activity.
十种植物地上部分的水提取物、乙醇提取物和丁醇粗提取物对四种细菌和两种真菌表现出不同程度的抗菌活性。水提取物对大肠杆菌、铜绿假单胞菌、蜡样芽孢杆菌、金黄色葡萄球菌、白色念珠菌和黄曲霉的抗菌活性较低。白骨壤水提取物表现出中等程度的抗真菌活性。乙醇提取物和丁醇粗提取物的抗菌活性有所提高。然而，与水提取物和乙醇提取物相比，丁醇提取物表现出更强的抗菌活性。与所测试的标准抗生素相比，丁醇提取物的活性最高。浓度为2000微克/圆片的白骨壤、嗜盐百脉根、香叶歧伞菊和刺山柑的丁醇提取物对革兰氏阳性菌和革兰氏阴性菌均具有很好的抗菌活性，对白色念珠菌和黄曲霉具有中等至良好的抗真菌活性。与标准氯霉素、四环素和萘啶酸相比，紫苜蓿、腋花补血草和香叶歧伞菊的丁醇粗提取物表现出更强的抗真菌活性。
