Jadhav Hemant R, Bhutani K K
Department of Natural Products, National Institute of Pharmaceutical Education and Research (NIPER), Sector 67, S. A. S. Nagar - 160 062 Punjab, India.
Phytother Res. 2002 Dec;16(8):771-3. doi: 10.1002/ptr.1063.
The antioxidant properties of methanol extracts of 12 Indian medicinal plants, traditionally used in disease areas that probably involve free radical mechanisms, were evaluated by two methods, namely the DPPH (1,1-diphenyl-2-picryl hydrazyl) test and the lipid peroxidation assay. In the latter assay, seven of these extracts showed 90% or more activity compared with the standard, vitamin E and hence were studied in detail after the removal of interfering pigments. The selective pigment removal from the extracts led to an increase in free radical scavenging activity and a decrease in inhibition of lipid peroxidation.
通过两种方法,即DPPH(1,1-二苯基-2-苦基肼)试验和脂质过氧化测定法,对12种印度药用植物甲醇提取物的抗氧化特性进行了评估,这些植物传统上用于可能涉及自由基机制的疾病治疗领域。在后者的测定中,与标准品维生素E相比,其中七种提取物显示出90%或更高的活性,因此在去除干扰色素后对其进行了详细研究。从提取物中选择性去除色素导致自由基清除活性增加,脂质过氧化抑制作用降低。