Chapin R E
Pfizer Global R&D, Drug Safety Evaluation, Eastern Point Rd., MS 8274-1336, Groton, Connecticut 06340, USA.
Hum Exp Toxicol. 2002 Sep-Oct;21(9-10):521-3. doi: 10.1191/0960327102ht291oa.
The benefits and costs are discussed for the possibility of using pups generated in breeding studies for additional assessments, such as evaluating immunotoxicity. Such an approach is logistically challenging, but not overwhelming.
对于在繁殖研究中产生的幼崽用于额外评估(如评估免疫毒性)的可能性,讨论了其益处和成本。这种方法在后勤方面具有挑战性,但并非不可克服。