Stephens Robert S, Babor Thomas F, Kadden Ronald, Miller Michael
Department of Psychology, Virginia Tech, Blacksburg, VA 24061, USA.
Addiction. 2002 Dec;97 Suppl 1:109-24. doi: 10.1046/j.1360-0443.97.s01.6.x.
Recent findings regarding the prevalence of marijuana dependence and associated consequences indicate the need for empirically validated treatments for this population. The Marijuana Treatment Project (MTP) was a multi-site study of two treatments for adults with marijuana dependence.
Participants (N= 450) were randomly assigned to one of three conditions at each of three sites: 1) a 9-session cognitive behavioral treatment (CBT) with motivational enhancement therapy (MET) and case management (CM) components; 2) a 2-session MET intervention; or 3) a delayed treatment control (DTC).
The study was conducted in outpatient drug treatment clinics in three U.S. cities.
Participants were individuals aged 18 or over who met diagnostic criteria for cannabis dependence and who voluntarily presented for treatment.
Study variables included DSM-IV dependence criteria, timeline follow-back assessment of drug use, Addiction Severity Index composite scores, and problems related to marijuana use.
Participants were daily users, who smoked marijuana multiple times per day, and had been doing so for more than 15 years. They reported multiple dependence symptoms and negative consequences related to marijuana use. Approximately 32% of the sample was female, and 30% of the sample was either Hispanic (17%), African American (12%), or of mixed racial backgrounds (1%).
The multi-site nature of the MTP allowed for the recruitment of a more ethnically and gender diverse sample than had been studied previously but there were few differences in the clinical characteristics of participants at the geographically and sociodemographically diverse study sites.
近期关于大麻依赖患病率及相关后果的研究结果表明,需要为这一人群提供经过实证验证的治疗方法。大麻治疗项目(MTP)是一项针对成年大麻依赖者的两种治疗方法的多地点研究。
参与者(N = 450)在三个地点中的每个地点被随机分配到三种条件之一:1)一种包含动机增强疗法(MET)和病例管理(CM)成分的9节认知行为疗法(CBT);2)一种2节的MET干预;或3)延迟治疗对照(DTC)。
该研究在美国三个城市的门诊药物治疗诊所进行。
参与者为年龄在18岁及以上、符合大麻依赖诊断标准且自愿前来接受治疗的个体。
研究变量包括《精神疾病诊断与统计手册》第四版(DSM-IV)的依赖标准、药物使用的时间线追溯评估、成瘾严重程度指数综合评分以及与大麻使用相关的问题。
参与者为每日使用者,每天吸食大麻多次,且已持续超过15年。他们报告了多种与大麻使用相关的依赖症状和负面后果。样本中约32%为女性,30%为西班牙裔(17%)、非裔美国人(12%)或混合种族背景(1%)。
MTP的多地点性质使得能够招募到比以往研究更多样化的种族和性别的样本,但在地理和社会人口统计学上不同的研究地点,参与者的临床特征几乎没有差异。