Tims Frank M, Dennis Michael L, Hamilton Nancy, J Buchan Betty, Diamond Guy, Funk Rod, Brantley Laura B
University of South Florida, USA.
Addiction. 2002 Dec;97 Suppl 1:46-57. doi: 10.1046/j.1360-0443.97.s01.7.x.
Risk factors among adolescent substance abusers have been shown to correlate with substance use severity. Characteristics related to severity, such as demographic and family factors, peer influences, psychiatric co-morbidity and HIV risk behaviors, are examined for a sample of adolescent cannabis users entering treatment.
These data are from a clinical trial study utilizing blocked random assignment of clients to one of five treatment conditions. The study targeted adolescents entering outpatient treatment for primarily cannabis abuse or dependence.
Treatment and research facilities in four metropolitan areas of the US were used to recruit study participants. Treatment was delivered in outpatient drug-free settings.
Participants were 600 clients, ages 12-18, admitted to outpatient substance abuse treatment programs for cannabis problems, 96% with DSM-IV diagnoses of substance abuse or dependence, with the remaining 4% having at least one symptom of dependence plus significant problems indicating need for treatment.
The Global Appraisal of Individual Needs (GAIN) was used to collect the information presented in this paper. The GAIN incorporates DSM-IV criteria for substance use disorders, conduct disorder and attention deficit hyperactivity disorder, as well as dimensional (scale) measures for physical and mental health.
All participants reported at least one symptom of substance use disorders, and 46% met the DSM-IV criteria for substance dependence, while 50% met criteria for a diagnosis of abuse. Only 20% of the participants perceived any need for help with problems associated with their drug or alcohol use. Clients participating in the study typically presented multiple problems at treatment entry, most often including conduct disorder, attention deficit hyperactivity disorder (ADHD), internal (mental) distress, and physical health distress. The co-occurrence of conduct disorder and ADHD was found in 30% of the sample. Clients meeting criteria for substance dependence tended to have more co-occurring problems and significantly less denial at admission.
The characteristics of this sample exemplify the complex nature of adolescent substance use and abuse among adolescents entering outpatient treatment programs. Patterns of co-occurring problems are at rates comparable to those found in other clinical studies. Those with more severe substance use disorders tend to manifest more problems of social functioning, more mental health problems, and physical health problems. Implications of these findings are discussed in terms of treatment needs, challenges, and prognostic implications.
研究表明,青少年药物滥用者的风险因素与药物使用严重程度相关。本文针对进入治疗的青少年大麻使用者样本,研究了与严重程度相关的特征,如人口统计学和家庭因素、同伴影响、精神疾病共病情况以及艾滋病病毒风险行为。
这些数据来自一项临床试验研究,该研究采用了将客户随机分配到五种治疗条件之一的区组随机化方法。该研究的对象是主要因大麻滥用或依赖而进入门诊治疗的青少年。
美国四个大都市地区的治疗和研究机构被用于招募研究参与者。治疗在无药物的门诊环境中进行。
参与者为600名年龄在12至18岁之间的客户,他们因大麻问题进入门诊药物滥用治疗项目,96%的人符合《精神疾病诊断与统计手册》第四版(DSM-IV)中药物滥用或依赖的诊断标准,其余4%的人至少有一项依赖症状以及表明需要治疗的严重问题。
本文所呈现的信息通过《个体需求综合评估》(GAIN)收集。GAIN纳入了DSM-IV中关于物质使用障碍、品行障碍和注意力缺陷多动障碍的标准,以及身心健康的维度(量表)测量。
所有参与者都报告了至少一项物质使用障碍症状,46%的人符合DSM-IV中物质依赖的标准,50%的人符合滥用诊断标准。只有20%的参与者意识到需要帮助解决与他们的药物或酒精使用相关的问题。参与研究的客户在进入治疗时通常存在多个问题,最常见的包括品行障碍、注意力缺陷多动障碍(ADHD)、内心(精神)困扰和身体健康困扰。30%的样本中发现品行障碍和ADHD共病。符合物质依赖标准的客户往往有更多的共病问题,且入院时否认问题的情况明显较少。
该样本的特征体现了进入门诊治疗项目的青少年中药物使用和滥用的复杂性。共病问题的模式与其他临床研究中的发生率相当。药物使用障碍更严重的人往往表现出更多的社会功能问题、更多的心理健康问题和身体健康问题。本文从治疗需求、挑战和预后影响等方面讨论了这些研究结果的意义。