James Julia, Carruthers Alastair, Carruthers Jean
Division of Dermatology and Department of Ophthalmology, University of British Columbia, Vancouver,British Columbia, Canada.
Dermatol Surg. 2002 Nov;28(11):979-86. doi: 10.1046/j.1524-4725.2002.02099.x.
HIV-infected individuals are living long, healthy lives. They are now concerned with less life-threatening problems, especially lipodystrophy.
To review the current state of our knowledge about lipodystrophy in HIV-infected individuals.
The literature was reviewed and analyzed for relevant information. In addition, our clinical experience of managing such individuals was utilized.
Lipodystrophy and facial lipoatrophy and their relationship to HIV-infection are discussed. Their differences are noted. The spectrum of appearance in individuals with facial lipoatrophy is described and a severity scale suggested which should be of value in assessing the results of treatment.
Lipodystrophy and lipoatrophy are intimately related to infection with HIV. In consequence, facial lipoatrophy is a major stigma for HIV-infected individuals and can have dramatic effects on their self-esteem and socialization. Effective treatment is essential.
感染HIV的个体正过着长寿且健康的生活。他们现在关注的是威胁性较小的问题，尤其是脂肪代谢障碍。
回顾我们目前对感染HIV个体脂肪代谢障碍的了解情况。
查阅并分析文献以获取相关信息。此外，还利用了我们管理此类个体的临床经验。
讨论了脂肪代谢障碍和面部脂肪萎缩及其与HIV感染的关系。指出了它们的差异。描述了面部脂肪萎缩个体的外观范围，并提出了一个严重程度量表，该量表在评估治疗结果时应具有价值。
脂肪代谢障碍和脂肪萎缩与HIV感染密切相关。因此，面部脂肪萎缩是感染HIV个体的一个主要耻辱标记，会对他们的自尊和社交产生巨大影响。有效治疗至关重要。
