Echavez Michael, Horstman William
University of California, San Francisco, USA.
AIDS Read. 2005 Jul;15(7):369-75.
An informal yet comprehensive literature review of abstracts published in Medline was undertaken to identify papers that reported on how facial aging, lipodystrophy, and facial lipoatrophy affect quality of life. Facial lipoatrophy can erode self-esteem, cause psychological distress, and lead to depression. Persons with HIV infection encounter both stigmatization and marginalization as a result of facial lipoatrophy. In addition to exploring novel antiretroviral therapies that do not result in lipodystrophy, clinicians should consider treatments that correct the appearance of lipoatrophy for patients who feel adversely affected by the condition.
我们对Medline上发表的摘要进行了一次非正式但全面的文献综述，以确定那些报告面部衰老、脂肪代谢障碍和面部脂肪萎缩如何影响生活质量的论文。面部脂肪萎缩会损害自尊，引起心理困扰，并导致抑郁。感染艾滋病毒的人会因面部脂肪萎缩而遭遇污名化和边缘化。除了探索不会导致脂肪代谢障碍的新型抗逆转录病毒疗法外，临床医生还应考虑为那些感觉受到该病症负面影响的患者提供能够改善脂肪萎缩外观的治疗方法。
