两例垂体腺瘤合并弓形虫感染的病例报告。
Two case reports of pituitary adenoma associated with Toxoplasma gondii infection.
作者信息
Zhang X, Li Q, Hu P, Cheng H, Huang G
机构信息
Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xi'An, Shaanxi Province, P R China, 710032.
出版信息
J Clin Pathol. 2002 Dec;55(12):965-6. doi: 10.1136/jcp.55.12.965.
Abstract
The involvement of the pituitary in cases of toxoplasmosis has been described in the literature only rarely. This is the first report to describe pituitary adenoma in association with Toxoplasma gondii infection. The two patients were 43 and 19 year old women. Radiological examination revealed tumours in the sellar region. Microscopically, the tumours consisted of small homogeneous polygonal or round cells. Toxoplasma cysts were found among the tumour cells, a finding confirmed by Toxoplasma gondii specific antibody immunohistochemistry. The association between pituitary adenoma and toxoplasma raises the possibility that T gondii might be involved in the development of certain cases of pituitary adenoma.
摘要
垂体在弓形虫病病例中的受累情况在文献中仅有极少的描述。这是首篇描述垂体腺瘤与刚地弓形虫感染相关的报告。两名患者分别为43岁和19岁女性。影像学检查显示蝶鞍区有肿瘤。显微镜下，肿瘤由小的均匀多边形或圆形细胞组成。在肿瘤细胞中发现了弓形虫囊肿，这一发现通过刚地弓形虫特异性抗体免疫组化得以证实。垂体腺瘤与弓形虫之间的关联增加了刚地弓形虫可能参与某些垂体腺瘤发生发展的可能性。
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