Stone Alan
International Family Health, Cityside House, 40 Adler Street, London E1 1EE, UK.
Nat Rev Drug Discov. 2002 Dec;1(12):977-85. doi: 10.1038/nrd959.
Many chemical agents can block human immunodeficiency virus (HIV) infection in the laboratory. Scientists are investigating which of these, used intravaginally by women, will safely prevent the sexual transmission of HIV in humans. Several such products - microbicides - will soon be tested in populations at high risk for HIV, and others are waiting in the wings. Microbicides will provide a low-cost method, controlled by women, for protection against HIV, other sexually transmitted pathogens and unwanted pregnancy, and will therefore have global public-health benefits.
在实验室中，许多化学制剂能够阻断人类免疫缺陷病毒（HIV）感染。科学家们正在研究其中哪些制剂经女性阴道使用后可安全预防HIV在人群中的性传播。有几种此类产品——杀微生物剂——很快将在HIV高危人群中进行测试，其他产品也已准备就绪。杀微生物剂将为女性提供一种低成本且由其自主控制的方法，用于预防HIV、其他性传播病原体以及意外怀孕，因而将带来全球公共卫生效益。
