泛素衍生出多个分支。

Ubiquitin branches out.

作者信息

Johnson Erica S

机构信息

Department of Biochemistry and Molecular Pharmacology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

出版信息

Nat Cell Biol. 2002 Dec;4(12):E295-8. doi: 10.1038/ncb1202-e295.

DOI:10.1038/ncb1202-e295

PMID:12461537

Abstract

In recent years, there has been a marked expansion of recognized roles for ubiquitin (Ub) in processes other than proteasome-dependent proteolysis, as well as a proliferation of Ub-like proteins that also function through covalent attachment to other proteins. The full diversity of functions for these proteins was on display at the American Society for Cell Biology (ASCB) meeting on "Non-Traditional Functions of Ubiquitin and Ubiquitin-Like Proteins" held at Colorado College in Colorado Springs, Colorado (August 11-14th, 2002).

摘要

近年来，泛素（Ub）在蛋白酶体依赖性蛋白水解以外的过程中所发挥的公认作用显著扩展，同时，通过与其他蛋白质共价连接发挥功能的类泛素蛋白也不断增多。这些蛋白质功能的多样性在2002年8月11日至14日于科罗拉多州科罗拉多斯普林斯的科罗拉多学院举行的美国细胞生物学学会（ASCB）“泛素和类泛素蛋白的非传统功能”会议上得到了充分展示。