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泛素介导的降解系统在植物生物学中的作用

Role of Ubiquitin-Mediated Degradation System in Plant Biology.

作者信息

Sharma Bhaskar, Joshi Deepti, Yadav Pawan K, Gupta Aditya K, Bhatt Tarun K

机构信息

Department of Biotechnology, School of Life Sciences, Central University of Rajasthan, Bandar Sindri Rajasthan, India.

出版信息

Front Plant Sci. 2016 Jun 8;7:806. doi: 10.3389/fpls.2016.00806. eCollection 2016.

Abstract

Ubiquitin-mediated proteasomal degradation is an important mechanism to control protein load in the cells. Ubiquitin binds to a protein on lysine residue and usually promotes its degradation through 26S proteasome system. Abnormal proteins and regulators of many processes, are targeted for degradation by the ubiquitin-proteasome system. It allows cells to maintain the response to cellular level signals and altered environmental conditions. The ubiquitin-mediated proteasomal degradation system plays a key role in the plant biology, including abiotic stress, immunity, and hormonal signaling by interfering with key components of these pathways. The involvement of the ubiquitin system in many vital processes led scientists to explore more about the ubiquitin machinery and most importantly its targets. In this review, we have summarized recent discoveries of the plant ubiquitin system and its involvement in critical processes of plant biology.

摘要

泛素介导的蛋白酶体降解是控制细胞内蛋白质负荷的重要机制。泛素与赖氨酸残基上的蛋白质结合,通常通过26S蛋白酶体系统促进其降解。许多过程的异常蛋白质和调节因子都被泛素-蛋白酶体系统靶向降解。它使细胞能够维持对细胞水平信号和变化的环境条件的反应。泛素介导的蛋白酶体降解系统通过干扰这些途径的关键成分,在植物生物学中发挥关键作用,包括非生物胁迫、免疫和激素信号传导。泛素系统参与许多重要过程,促使科学家更多地探索泛素机制,最重要的是其靶标。在本综述中,我们总结了植物泛素系统的最新发现及其在植物生物学关键过程中的参与情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b36d/4897311/6f777fd9c868/fpls-07-00806-g001.jpg

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