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高能光子束在建成区蒙特卡罗计算与测量之间的剂量差异。

Dose discrepancies between Monte Carlo calculations and measurements in the buildup region for a high-energy photon beam.

作者信息

Ding George X

机构信息

Medical Physics, Fraser Valley Cancer Centre, British Columbia Cancer Agency, Surrey, BC, V3V 1Z2 Canada.

出版信息

Med Phys. 2002 Nov;29(11):2459-63. doi: 10.1118/1.1514237.

Abstract

This study investigates a possible cause of reported significant dose discrepancies between Monte Carlo calculations and measurements in the buildup region for high-energy photon beams in large fields. A proposed hypothesis was that the discrepancy was caused by a source of electrons in the accelerator head that was not fully accounted for in the treatment head simulation. In this investigation, a lead foil is added just below the accelerator head in order to study this hypothesis. The lead foil effectively removes charged particles generated inside the accelerator head. The charged particles generated by the lead foil can be accounted for fully because the simple geometry can be simulated accurately. An 18 MV photon beam from a Varian Clinac-2100EX is measured using a WELLHOFER WP700 beam scanner with an IC-10 ionization chamber (cavity radius=3 mm). The BEAM Monte Carlo code is used in the incident beam simulations. Both EGS4/DOSXYZ and EGSnrc/DOSRZnrc are used in the dose calculations in a water phantom. The Monte Carlo calculated depth-dose curve is scaled so that it has the same values at 10 cm depth as the measured curve. It is found that the discrepancies between Monte Carlo calculations and measurements remain significant in the buildup region even after applying necessary corrections to the measured data. The discrepancies have only been modestly decreased with the lead foil in place compared to the 40 x 40 cm2 open field. At a depth of 1 cm, discrepancies of about 5% are still observed in the buildup region for the field with the lead foil. Therefore a new explanation for the unresolved discrepancy remains to be found.

摘要

本研究调查了在大射野高能光子束的剂量建成区,蒙特卡罗计算结果与测量值之间出现显著剂量差异的一个可能原因。提出的假设是,这种差异是由加速器头部中一个在治疗头模拟中未被充分考虑的电子源引起的。在这项研究中,在加速器头部正下方添加了一块铅箔,以研究这一假设。铅箔有效地去除了加速器头部内部产生的带电粒子。由于简单的几何形状能够被精确模拟,因此由铅箔产生的带电粒子能够被完全考虑在内。使用配备IC - 10电离室(腔半径 = 3 mm)的WELLHOFER WP700束流扫描仪,对Varian Clinac - 2100EX产生的18 MV光子束进行测量。在入射束模拟中使用BEAM蒙特卡罗代码。在水模体的剂量计算中同时使用了EGS4/DOSXYZ和EGSnrc/DOSRZnrc。对蒙特卡罗计算得到的深度剂量曲线进行缩放,使其在10 cm深度处与测量曲线具有相同的值。结果发现,即使对测量数据进行了必要的校正,在剂量建成区,蒙特卡罗计算结果与测量值之间的差异仍然很大。与40×40 cm²开放射野相比,在放置铅箔后差异仅略有减小。在1 cm深度处,对于放置铅箔的射野在剂量建成区仍观察到约5%的差异。因此,仍有待找到对未解决差异的新解释。

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