Gorrel C, Larsson A
Department of Oral Pathology, Centre for Oral Health Sciences, Malmö University, Sweden.
J Small Anim Pract. 2002 Nov;43(11):482-8. doi: 10.1111/j.1748-5827.2002.tb00018.x.
The purpose of this study was to increase understanding of the factors initiating feline odontoclastic resorptive lesions (FORLs). Fifty-six teeth (clinically and radiographically unaffected by ORLs) were harvested. Of these, 43 were from cats that had ORLs in other teeth (group A) and 13 were from cats with no clinical or radiographic evidence of ORLs in any teeth (group B). Twenty-six teeth in group A and one tooth in group B showed histological evidence of external root resorption (surface resorption and replacement resorption resulting in ankylosis). Some teeth in group B showed healed cementum resorption. It has previously been assumed that FORLs were similar to lesions associated with peripheral inflammatory root resorption, and were associated with periodontal disease. These histological findings suggest instead that a FORL is a non-inflammatory replacement resorption, resulting in ankylosis. The periodontal ligament of resorbing teeth lacked normal fibrous architecture, but was not inflamed. Resorption was not identified in cervical cementum. However, the histological appearance of the cervical cementum differed between the two groups. Several aetiopathogenetic explanatory models which arise from these observations are discussed.
本研究的目的是增进对引发猫牙骨质吸收性病变（FORLs）的因素的理解。采集了56颗牙齿（临床和影像学检查未受ORLs影响）。其中，43颗来自其他牙齿患有ORLs的猫（A组），13颗来自任何牙齿均无临床或影像学ORLs证据的猫（B组）。A组中的26颗牙齿和B组中的1颗牙齿显示出外部牙根吸收的组织学证据（表面吸收和替代吸收导致牙根粘连）。B组中的一些牙齿显示出愈合的牙骨质吸收。此前一直认为FORLs与外周炎性牙根吸收相关的病变相似，且与牙周疾病有关。相反，这些组织学发现表明FORL是一种非炎性替代吸收，导致牙根粘连。正在吸收的牙齿的牙周膜缺乏正常的纤维结构，但未发炎。在颈部牙骨质中未发现吸收。然而，两组之间颈部牙骨质的组织学外观有所不同。讨论了基于这些观察结果产生的几种病因病理解释模型。
