de Zwart Jacco A, van Gelderen Peter, Kellman Peter, Duyn Jeff H
Advanced MRI, Laboratory of Functional and Molecular Imaging, NINDS, National Institutes of Health, Bethesda, Maryland 20892-1065, USA.
Magn Reson Med. 2002 Dec;48(6):1011-20. doi: 10.1002/mrm.10303.
The benefits of sensitivity-encoded (SENSE) echo-planar imaging (EPI) for functional MRI (fMRI) based on blood oxygen level-dependent (BOLD) contrast were quantitatively investigated at 1.5 T. For experiments with 3.4 x 3.4 x 4.0 mm(3) resolution, SENSE allowed the single-shot EPI image acquisition duration to be shortened from 24.1 to 12.4 ms, resulting in a reduced sensitivity to geometric distortions and T(*)(2) blurring. Finger-tapping fMRI experiments, performed on eight normal volunteers, showed an overall 18% loss in t-score in the activated area, which was substantially smaller than expected based on the image signal-to-noise ratio (SNR) and g-factor, but similar to the loss predicted by a model that takes physiologic noise into account.
在1.5T磁场下，对基于血氧水平依赖（BOLD）对比的功能磁共振成像（fMRI）中，敏感性编码（SENSE）回波平面成像（EPI）的益处进行了定量研究。对于分辨率为3.4×3.4×4.0 mm³的实验，SENSE使单次激发EPI图像采集时间从24.1毫秒缩短至12.4毫秒，从而降低了对几何畸变和T*₂模糊的敏感性。对八名正常志愿者进行的手指轻敲fMRI实验显示，激活区域的t分数总体损失了18%，这比基于图像信噪比（SNR）和g因子预期的要小得多，但与考虑生理噪声的模型预测的损失相似。
