Fukuda Mamoru, Miyamoto Keiko, Hashizume Rintaro, Okamoto Jyoji, Kawamoto Hisanori, Yabuki Yukari, Ogata Haruki, Ohta Tomohiko
Division of Breast and Endocrine Surgery, St. Marianna University School of Medicine.
Gan To Kagaku Ryoho. 2002 Nov;29(11):1900-6.
In Japan the mortality and incidence rates of breast cancer have been increasing. In 2000, the number of breast cancer deaths in female was 9,171. In 1996, the aged adjusted incidence rate of breast cancer was 38.9, top among all of female cancers and the estimated number of female breast cancer patients was 29,448 in Japan. Therefore, efficient breast cancer screening system is urgently needed. In April 2000, breast screening using biennial mammography in combination with clinical breast examination instead of annual clinical breast examination alone was introduced for women aged 50 and over in Japan. However, the compliance of screening using mammography was less than 1% in the fiscal 2000 year. On the other hand, the compliance of screening with clinical breast examination alone was 6.5% in same period. These compliances were significantly lower than that of about 65% in the USA. Given the importance of the control of quality in screening mammography, a central committee for the quality control of mammographic screening has been established in order to educate doctors and radiographers and to assess image apparatus in each facility. As of April 2002, 1,409 out of 1,978 doctors that participated in the training program had obtained either grade A (instructor level) or grade B (adequate level). Gøtzche and Olsen reassessed previous meta-analyses of screening mammography and concluded that screening for breast cancer with mammography was unjustified. Subsequently, reviews by U. S. Preventive Services Task Forces and the WHO reconfirmed the effectiveness of screening mammography in reducing breast cancer mortality. These controversies show the importance of assessment of screening mammography effectiveness in Japan.
在日本,乳腺癌的死亡率和发病率一直在上升。2000年,女性乳腺癌死亡人数为9171人。1996年,乳腺癌的年龄调整发病率为38.9,在所有女性癌症中位居榜首,日本女性乳腺癌患者估计人数为29448人。因此,迫切需要高效的乳腺癌筛查系统。2000年4月,日本开始对50岁及以上女性采用每两年一次的乳房X线摄影检查结合临床乳房检查,取代以往单独的年度临床乳房检查。然而,2000财年乳房X线摄影检查的筛查依从率不到1%。另一方面,同期单独进行临床乳房检查的筛查依从率为6.5%。这些依从率明显低于美国约65%的水平。鉴于乳房X线摄影筛查质量控制的重要性,已成立了乳房X线摄影筛查质量控制中央委员会,以培训医生和放射技师,并对各机构的影像设备进行评估。截至2002年4月,参加培训项目的1978名医生中,有1409人获得了A级(指导教师级别)或B级(合格级别)。戈茨彻和奥尔森重新评估了以往关于乳房X线摄影筛查的荟萃分析,得出结论认为,用乳房X线摄影筛查乳腺癌是不合理的。随后,美国预防服务工作组和世界卫生组织的审查再次证实了乳房X线摄影筛查在降低乳腺癌死亡率方面的有效性。这些争议表明了在日本评估乳房X线摄影筛查有效性的重要性