小脑炎的质子磁共振波谱分析

Proton MR spectroscopy of cerebellitis.

作者信息

Guerrini Laura, Belli Giacomo, Cellerini Martino, Nencini Patrizia, Mascalchi Mario

机构信息

Radiodiagnostica I, Dipartimento di Fisiopatologia Clinica, Università di Firenze, Viale Morgagni 85, Italy.

出版信息

Magn Reson Imaging. 2002 Oct;20(8):619-22. doi: 10.1016/s0730-725x(02)00600-8.

DOI:10.1016/s0730-725x(02)00600-8

PMID:12467871

Abstract

Single voxel proton MR spectroscopy ((1)H-MRS) of the vermis was obtained in two patients with cerebellitis. In the acute phase (1)H-MRS revealed low N-acetyl-aspartate (NAA)/creatine (Cr) and NAA/choline (Cho) and normal Cho/Cr ratios. Decrease of the concentration of NAA was confirmed by quantitative analysis in one patient. The NAA/Cr and NAA/Cho ratios and NAA concentration were increased in (1)H-MRS examinations obtained 10 and 24 months after the acute episode. (1)H-MRS demonstrates reversible metabolite changes in cerebellitis.

摘要

对两名患有小脑炎的患者进行了蚓部的单体素质子磁共振波谱分析（¹H-MRS）。在急性期，¹H-MRS显示N-乙酰天门冬氨酸（NAA）/肌酸（Cr）和NAA/胆碱（Cho）降低，而Cho/Cr比值正常。一名患者的定量分析证实了NAA浓度降低。在急性期发作后10个月和24个月进行的¹H-MRS检查中，NAA/Cr和NAA/Cho比值以及NAA浓度均升高。¹H-MRS显示小脑炎中代谢物变化是可逆的。