Bosseray A, Bonadona A, Morand P
Département pluridisciplinaire de Médecine, CHU Grenoble, 38043 Grenoble, France.
Pathol Biol (Paris). 2002 Oct;50(8):483-92. doi: 10.1016/s0369-8114(02)00339-5.
Herpes simplex viruses (HSV) can cause a variety of infections, including genital herpes. Despite effective antiviral therapy HSV infections remain a public health problem. Vaccines offer the possibility for controlling the spread and limiting HSV disease, two strategies for herpes vaccination: prophylactic immunization or therapeutic immunization. The article discusses the results of different studies, in particular, concerning recombinant vaccines, DISC vaccines and DNA vaccines.
单纯疱疹病毒（HSV）可引起多种感染，包括生殖器疱疹。尽管有有效的抗病毒疗法，但HSV感染仍然是一个公共卫生问题。疫苗为控制传播和限制HSV疾病提供了可能性，疱疹疫苗接种有两种策略：预防性免疫或治疗性免疫。本文讨论了不同研究的结果，特别是关于重组疫苗、DISC疫苗和DNA疫苗的研究结果。
