Sahin Günsah, Duce Meltem Nass, Milcan Abtullah, Bagis Selda, Cimen Ozlem Bölgen, Cimen Burak, Erdogan Canan
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Mersin University, Mersin, Turkey.
Int J Fertil Womens Med. 2002 Sep-Oct;47(5):236-9.
To assess the relationship of grip strength to site-specific bone mineral density of the metacarpal bone and also axial bone mineral density. The bone mineral density of the lumbar spine, femoral neck and the nondominant hand were measured by DEXA.
A total of 187 postmenopausal women were included in the study. Of the patients, 102 were osteoporotic, and 85 were not osteoporotic and served as control subjects.
Grip strength of the nondominant hand was measured by hand-held dynamometer. Skinfold thickness of the nondominant hand was measured by a caliper (Holstain). Biochemical markers of bone turnover and other osteoporosis-related variables were also measured.
There was a statistically significant difference between groups regarding bone mineral density of the lumbar, femoral (neck) and hand regions and the grip strength (P < .05). Hand bone mineral density (BMD) was found to be correlated with bone mineral density of the lumbar and femoral (neck) regions in osteoporotic patients. Grip strength was correlated positively with the BMD of the nondominant hand. Grip strength was correlated negatively with age and years since menopause. Grip strength was also correlated positively with femoral neck BMD.
The study provides support for a site-specific and also systemic relationship between muscle and bone. Grip strength is also a predictor of hand bone mineral density.
评估握力与掌骨特定部位骨密度以及轴向骨密度之间的关系。采用双能X线吸收法（DEXA）测量腰椎、股骨颈和非优势手的骨密度。
本研究共纳入187名绝经后女性。其中102例为骨质疏松症患者，85例非骨质疏松症患者作为对照。
使用手持式测力计测量非优势手的握力。用卡尺（霍尔斯坦）测量非优势手的皮褶厚度。还测量了骨转换的生化标志物和其他与骨质疏松症相关的变量。
两组在腰椎、股骨（颈）和手部区域的骨密度以及握力方面存在统计学显著差异（P < 0.05）。在骨质疏松症患者中，发现手部骨密度（BMD）与腰椎和股骨（颈）区域的骨密度相关。握力与非优势手的BMD呈正相关。握力与年龄和绝经年限呈负相关。握力也与股骨颈BMD呈正相关。
该研究为肌肉与骨骼之间的特定部位及全身关系提供了支持。握力也是手部骨密度的一个预测指标。
