Sinaki M, Wahner H W, Offord K P
Department of PM&R, Mayo Clinic, Rochester, MN 55905.
Arch Phys Med Rehabil. 1989 Nov;70(12):823-6.
This study of postmenopausal women had two objectives: (1) to determine whether there is a correlation between the strength of grip muscles and bone mineral content in the midradius where these muscles attach, and (2) to determine whether this correlation is of sufficient magnitude to predict cortical bone content by measuring grip muscle strength. Nondominant power grip and bone mineral content of the midradius were measured in 63 healthy postmenopausal Caucasian women. Significant positive correlations (p less than 0.001) were noted between regional bone mineral content and nondominant power grip, and significant negative correlations (p less than 0.001) were found between nondominant power grip and age and between regional bone mineral content and age. When bone mineral data were normalized for skeletal size, there was no significant improvement of the correlation. In addition, the correlation between grip strength and bone mineral content at the midradius was not sufficiently strong to permit the use of grip strength measurements for prediction of midradius bone mineral content for clinical decision-making or epidemiologic studies. Furthermore, the correlation between grip strength and bone mineral content at the muscle insertion site was not better than the correlation between grip strength and bone mineral content at more distal sites on the same bone.
（1）确定握力肌肉的力量与这些肌肉附着处的桡骨中段骨矿物质含量之间是否存在相关性；（2）确定这种相关性是否足够大，以便通过测量握力肌肉力量来预测皮质骨含量。对63名健康的绝经后白人女性测量了非优势手的强力握力和桡骨中段的骨矿物质含量。区域骨矿物质含量与非优势手强力握力之间存在显著正相关（p<0.001），非优势手强力握力与年龄之间以及区域骨矿物质含量与年龄之间存在显著负相关（p<0.001）。当对骨骼大小进行骨矿物质数据标准化时，相关性没有显著改善。此外，握力与桡骨中段骨矿物质含量之间的相关性不够强，无法用于临床决策或流行病学研究中通过握力测量来预测桡骨中段骨矿物质含量。此外，肌肉附着部位的握力与骨矿物质含量之间的相关性并不优于同一骨骼更远端部位的握力与骨矿物质含量之间的相关性。
