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种族与外周血管疾病

Ethnicity and peripheral vascular disease.

作者信息

Makin A J, Silverman S H, Lip G Y H

机构信息

University Department of Medicine, City Hospital, Birmingham.

出版信息

Int J Clin Pract. 2002 Nov;56(9):645-8.

Abstract

There are well-documented differences in the prevalence of coronary artery disease and carotid disease between caucasians, Afro-Caribbeans and Indo-Asians. Very little data are available on ethnic differences in peripheral vascular disease (PVD). To investigate this further, we surveyed 200 consecutive patients attending the vascular surgery service at a city centre hospital serving a multiethnic patient catchment population. All patients had proven PVD, with an ankle brachial pressure index of less than 0.8. Within this cohort, Afro-Caribbeans presented more frequently with PVD compared with the proportion of this ethnic group in the local population (p = 0.013), with a greater proportion with diabetes mellitus than in the other two ethnic groups. There did not appear to be a significant difference between the ethnic groups in any of the other established risk factors or associations (i.e. treated hypertension, smoking, previous history of ischaemic heart disease, atrial fibrillation, previous history of cerebrovascular accident or transient ischaemic attack) with PVD. As with coronary artery disease and carotid disease, there are ethnic differences in the prevalence of PVD, and the underlying risk factors, between caucasians, Afro-Caribbeans and Indo-Asians. Furthermore, patients of Afro-Caribbean origin present more frequently with symptomatic PVD than do either caucasians or Indo-Asians.

摘要

白种人、非洲裔加勒比人和印裔亚洲人在冠状动脉疾病和颈动脉疾病的患病率方面存在有充分文献记载的差异。关于外周血管疾病(PVD)种族差异的数据非常少。为了进一步研究这一问题,我们对一家市中心医院血管外科服务的200名连续就诊患者进行了调查,该医院服务于多民族患者群体。所有患者均确诊患有PVD,踝臂压力指数小于0.8。在这个队列中,与该种族在当地人口中的比例相比,非洲裔加勒比人患PVD的比例更高(p = 0.013),患糖尿病的比例也高于其他两个种族。在其他已确定的危险因素或关联因素(即治疗过的高血压、吸烟、缺血性心脏病病史、心房颤动、脑血管意外或短暂性脑缺血发作病史)方面,各民族之间与PVD似乎没有显著差异。与冠状动脉疾病和颈动脉疾病一样,白种人、非洲裔加勒比人和印裔亚洲人在PVD患病率及潜在危险因素方面存在种族差异。此外,非洲裔加勒比裔患者出现有症状PVD的频率高于白种人和印裔亚洲人。

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