Heimbecker R, Robert A, McKenzie F N
Ann Thorac Surg. 1976 Jan;21(1):55-8. doi: 10.1016/s0003-4975(10)64888-6.
An arterial line filter can become a grave source of platelet and fibrin destruction, with widespread deposition on the filter to form a membrane across the mesh, as proved by careful scanning electron microscopy. The same filter, when subjected to the low flows of the cardiotomy line, was well tolerated and served a very useful function. There was a 260% improvement in platelet counts and a 170% reduction in chest drainage when the arterial line filter was not used, perhaps through elimination of a degree of consumptive coagulopathy. Neurological changes did not occur in the absence of the arterial line filter, and operative mortality was 4.8% (5 of 103 patients).
动脉滤器可能成为血小板和纤维蛋白严重破坏的来源，通过仔细的扫描电子显微镜观察证实，血小板和纤维蛋白会广泛沉积在滤器上，在网孔间形成一层膜。同样的滤器，在心内直视手术管路低流量情况下，耐受性良好且发挥了非常有用的功能。不使用动脉滤器时，血小板计数提高了260%，胸腔引流量减少了170%，这可能是因为消除了一定程度的消耗性凝血病。在没有动脉滤器的情况下未出现神经功能改变，手术死亡率为4.8%（103例患者中有5例）。
