Okies J E, Page U S, Bigelow J C, Krause A H, Salomon N W, Laxer K L
Good Samaritan Hospital and Medical Center, Portland, Oregon, USA.
Tex Heart Inst J. 1986 Mar;13(1):97-104.
Currently it is possible to account for an incidence of perfusion-related perioperative stroke of about 1%. The sources of stroke over which cardiac surgeons have some control relate to the perfusion circuit, the conducting of coronary pulmonary bypass, the operative approach to the patient with intracardiac clot, maneuvers that eliminate air during left heart procedures, control of biochemical factors such as hyperglycemia, and to the choice of anesthetic agents and drugs given during the procedure. The availability of equipment that allows in-line continuous monitoring of arterial and venous O2 saturations, control of physiologic parameters within certain limits, selective use of encephalographic monitoring for high-risk patients, along with careful attention to the details of the procedure, may allow the surgeon to alter favorably the numbers of patients suffering neurologic complications as a consequence of cardiac surgery. We have limited our investigation in this study to those neurologic events occurring from the onset of anesthesia through the recovery from anesthesia when the patient can be neurologically examined.
目前,灌注相关围手术期卒中的发生率约为1%。心脏外科医生能够控制的卒中来源与体外循环回路、冠状动脉搭桥手术的实施、有心内血栓患者的手术入路、左心手术期间消除空气的操作、对高血糖等生化因素的控制以及手术期间麻醉剂和药物的选择有关。能够对动脉和静脉血氧饱和度进行在线连续监测、在一定限度内控制生理参数、对高危患者选择性使用脑电图监测的设备,再加上对手术细节的密切关注,可能会使外科医生能够有效降低心脏手术导致神经并发症的患者数量。在本研究中,我们将调查局限于从麻醉开始到患者能够接受神经学检查的麻醉恢复阶段所发生的神经事件。