Marzluff William F, Duronio Robert J
Program in Molecular Biology and Biotechnology, University of North Carolina, Chapel Hill, NC 27599, USA.
Curr Opin Cell Biol. 2002 Dec;14(6):692-9. doi: 10.1016/s0955-0674(02)00387-3.
Histone mRNA metabolism is tightly coupled to cell cycle progression and to rates of DNA synthesis. The recent identification of several novel proteins involved in histone gene transcription and pre-mRNA processing has shed light on the variety of mechanisms cells employ to achieve this coupling.
组蛋白mRNA代谢与细胞周期进程以及DNA合成速率紧密相关。最近对几种参与组蛋白基因转录和前体mRNA加工的新型蛋白质的鉴定，揭示了细胞用来实现这种关联的多种机制。
