Högl B, Frauscher B, Seppi K, Ulmer H, Poewe W
Department of Neurology, University of Innsbruck, Austria.
Neurology. 2002 Dec 10;59(11):1705-7. doi: 10.1212/01.wnl.0000036606.56405.3d.
To assess the incidence and time course of new-onset restless legs syndrome (RLS) after spinal anesthesia.
A total of 202 consecutive patients undergoing spinal anesthesia for various types of surgery were prospectively evaluated regarding the presence and severity of RLS symptoms 48 to 72 hours post surgery and after 1 week, 1 month, 3 months, and 6 months. A diagnosis of RLS was made according to the criteria of the International RLS Study Group (IRLSSG), and severity was assessed by the IRLSSG severity scale.
Of 161 patients without any history of RLS, 8.7% developed first-onset RLS after spinal anesthesia. Symptoms were transient, with a mean duration of 33 +/- 30 days. Low mean corpuscular volume and mean corpuscular hemoglobin were associated with the occurrence of new-onset RLS after spinal anesthesia.
Transient RLS can be induced by spinal anesthesia. The mechanisms by which spinal anesthesia can trigger RLS are unclear but may include deficits in spinal sensorimotor integration in susceptible individuals.
评估脊髓麻醉后新发不安腿综合征（RLS）的发生率及病程。
对连续202例因各类手术接受脊髓麻醉的患者进行前瞻性评估，观察术后48至72小时以及术后1周、1个月、3个月和6个月时RLS症状的存在情况及严重程度。根据国际不安腿综合征研究组（IRLSSG）的标准进行RLS诊断，并通过IRLSSG严重程度量表评估严重程度。
在161例无RLS病史的患者中，8.7%在脊髓麻醉后出现首发RLS。症状为短暂性，平均持续时间为33±30天。低平均红细胞体积和平均红细胞血红蛋白与脊髓麻醉后新发RLS的发生有关。
脊髓麻醉可诱发短暂性RLS。脊髓麻醉引发RLS的机制尚不清楚，但可能包括易感个体脊髓感觉运动整合功能缺陷。
