Fidler M W, Jowett R L, Troup J D
J Bone Joint Surg Br. 1975 May;57(2):220-7.
Biopsies of lumbar multifidus muscles were obtained at operation on seventeen patients aged from fifteen to fifty-eight with lumbar spinal derangement, and further material was taken from the cadavers of three subjects aged from nineteen to fifty-one. Sections were prepared to show the presence of ATPase activity, so distinguishing Fast from Slow types of muscle fibre. The normal mosiac pattern arising from the intermingling of fibres from Fast and Slow motor units was seen in sections from cadaveric material and from many of the biopsies. With age and limited lumbar flexibility, the Fast fibres became relatively smaller but with increasing variation in size, suggesting a reduced capacity for phasic activity. The presence of positive root signs was associated with a greater proportion of Slow fibres, and in some patients with the occurrence of atrophied Fast fibres, giving rise to differences in the populations of the two fibres in neighbouring fascicles. The results suggest that multifidus adopts an increasingly postural role with advancing age and with disabling lesions of the lumbar spine.
对17例年龄在15岁至58岁之间患有腰椎紊乱症的患者在手术中获取了腰多裂肌活检样本，并从3名年龄在19岁至51岁之间的受试者尸体上获取了更多样本。制备切片以显示ATP酶活性的存在，从而区分快肌纤维和慢肌纤维类型。在尸体样本和许多活检样本的切片中都观察到了由快肌运动单位和慢肌运动单位的纤维混合形成的正常镶嵌模式。随着年龄增长和腰椎灵活性受限，快肌纤维相对变小，但大小差异增大，提示相性活动能力下降。阳性神经根体征的存在与慢肌纤维比例较高相关，在一些患者中还出现了萎缩的快肌纤维，导致相邻肌束中两种纤维的数量存在差异。结果表明，随着年龄增长和腰椎的致残性病变，多裂肌越来越多地发挥姿势性作用。
