Friedmann Peter S
Dermatopharmacology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD.
Hosp Med. 2002 Nov;63(11):653-6. doi: 10.12968/hosp.2002.63.11.1909.
Atopic eczema is associated with a genetic predisposition to dysregulation of the immune system. T lymphocytes differentiate towards the Th2 type with promotion of immunoglobulin E antibodies. Allergic responses to environmental allergens develop and microbes, including staphylococci and pityrosporum yeasts, may contribute to the inflammatory process.