Mester J, Vadász I, Pataki G, Parsons L, Fodor T, Salfinger M, Somoskövi A
3rd Department, Koranyi National Institute for Tuberculosis and Respiratory Medicine, Budapest, Hungary.
Int J Tuberc Lung Dis. 2002 Nov;6(11):966-73.
Hungary, Central Europe, with a population of 10.3 million living in 20 administrative districts (19 counties and the capital).
To summarize the results of the first year of the revised National Tuberculosis Surveillance System.
Retrospective survey of the National Tuberculosis Surveillance Center (NTSC) database.
Analysis of data on all tuberculosis cases reported to the NTSC in 2000. Drug susceptibility results were evaluated in line with WHO and IUATLD definitions.
During 2000, a total of 3598 patients with tuberculosis were reported. Only 40% of these were bacteriologically confirmed. Although susceptibility testing has been required for previously untreated culture-positive cases, only 801 (67.8% of the bacteriologically confirmed cases) were tested in 2000. Drug resistance was detected in 10.7% of previously untreated and in 23.5% of previously treated patients. Multidrug-resistant (MDR) cases were not common: only 1.5% of the isolates from previously untreated patients and 4.9% of those from previously treated patients were MDR.
The results suggest that the NTSC should work towards increasing the numbers of cases that are bacteriologically confirmed. In addition, some form of surveillance system should be instituted to ensure that mandatory susceptibility testing is performed on all isolates from previously untreated tuberculosis patients.
匈牙利位于中欧,有1030万人口,分布在20个行政区(19个县和首都)。
总结修订后的国家结核病监测系统第一年的结果。
对国家结核病监测中心(NTSC)数据库进行回顾性调查。
分析2000年向NTSC报告的所有结核病病例的数据。根据世界卫生组织和国际防痨和肺部疾病联盟的定义对药敏结果进行评估。
2000年共报告了3598例结核病患者。其中只有40%经细菌学确诊。尽管以前未经治疗的培养阳性病例需要进行药敏试验,但2000年只有801例(占细菌学确诊病例的67.8%)进行了检测。在以前未经治疗的患者中,耐药率为10.7%,在以前接受过治疗的患者中为23.5%。耐多药(MDR)病例并不常见:以前未经治疗患者的分离株中只有1.5%是耐多药的,以前接受过治疗患者的分离株中为4.9%。
结果表明,NTSC应努力增加细菌学确诊病例的数量。此外,应建立某种形式的监测系统,以确保对以前未经治疗的结核病患者的所有分离株进行强制性药敏试验。