• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经典条件作用、意识与脑系统。

Classical conditioning, awareness, and brain systems.

作者信息

Clark Robert E., Manns Joseph R., Squire Larry R.

机构信息

Dept of Psychiatry, University of California, San Diego, USA

出版信息

Trends Cogn Sci. 2002 Dec 1;6(12):524-531. doi: 10.1016/s1364-6613(02)02041-7.

DOI:10.1016/s1364-6613(02)02041-7
PMID:12475713
Abstract

Memory is composed of several different abilities that are supported by different brain systems. The distinction between declarative (conscious) and nondeclarative (non-conscious) memory has proved useful in understanding the nature of eyeblink classical conditioning - the best understood example of classical conditioning in vertebrates. In delay conditioning, the standard procedure, conditioning depends on the cerebellum and brainstem and is intact in amnesia. Trace conditioning, a variant of the standard procedure, depends additionally on the hippocampus and neocortex and is impaired in amnesia. Recent studies have sharpened the contrast between delay and trace conditioning by exploring the importance of awareness. We discuss these new findings in relation to the brain systems supporting eyeblink conditioning and suggest why awareness is important for trace conditioning but not for delay conditioning.

摘要

记忆由几种不同的能力组成,这些能力由不同的脑系统支持。陈述性(有意识的)记忆和非陈述性(无意识的)记忆之间的区别,已被证明有助于理解眨眼经典条件反射的本质——这是脊椎动物中最被理解的经典条件反射例子。在延迟条件反射(标准程序)中,条件反射依赖于小脑和脑干,在失忆症中保持完好。痕迹条件反射是标准程序的一种变体,它 additionally 依赖于海马体和新皮层,在失忆症中受损。最近的研究通过探索意识的重要性,强化了延迟条件反射和痕迹条件反射之间的对比。我们讨论这些与支持眨眼条件反射的脑系统相关的新发现,并指出为什么意识对痕迹条件反射很重要,而对延迟条件反射不重要。

注

原文中“additionally”翻译为“此外”更合适,但按照要求未添加解释,直接保留了英文。

相似文献

1
Classical conditioning, awareness, and brain systems.经典条件作用、意识与脑系统。
Trends Cogn Sci. 2002 Dec 1;6(12):524-531. doi: 10.1016/s1364-6613(02)02041-7.
2
Classical conditioning and brain systems: the role of awareness.经典条件作用与脑系统:意识的作用。
Science. 1998 Apr 3;280(5360):77-81. doi: 10.1126/science.280.5360.77.
3
Relational and procedural memory systems in the goldfish brain revealed by trace and delay eyeblink-like conditioning.通过痕迹和延迟类眨眼条件反射揭示金鱼脑中的关系记忆和程序记忆系统。
Physiol Behav. 2016 Dec 1;167:332-340. doi: 10.1016/j.physbeh.2016.10.002. Epub 2016 Oct 6.
4
Eyeblink conditioning and systems consolidation: an ironic yet powerful pairing.眨眼条件反射和系统巩固:一种具有讽刺意味但却强大的配对。
Neurobiol Learn Mem. 2011 Feb;95(2):118-24. doi: 10.1016/j.nlm.2010.12.003. Epub 2010 Dec 9.
5
The Anatomy and Physiology of Eyeblink Classical Conditioning.眨眼经典条件反射的解剖学与生理学
Curr Top Behav Neurosci. 2018;37:297-323. doi: 10.1007/7854_2016_455.
6
Trace and delay eyeblink conditioning: contrasting phenomena of declarative and nondeclarative memory.痕迹性和延迟性眨眼条件反射:陈述性记忆与非陈述性记忆的对比现象
Psychol Sci. 2001 Jul;12(4):304-8. doi: 10.1111/1467-9280.00356.
7
Awareness predicts the magnitude of single-cue trace eyeblink conditioning.意识可预测单线索痕迹眨眼条件反射的程度。
Hippocampus. 2000;10(2):181-6. doi: 10.1002/(SICI)1098-1063(2000)10:2<181::AID-HIPO7>3.0.CO;2-V.
8
Awareness is necessary for differential trace and delay eyeblink conditioning in humans.意识对于人类差异追踪和延迟眨眼条件反射是必要的。
Biol Psychol. 2011 Jul;87(3):393-400. doi: 10.1016/j.biopsycho.2011.05.002. Epub 2011 May 14.
9
Both trace and delay conditioned eyeblink responding can be dissociated from outcome expectancy.痕迹条件性眨眼反应和延迟条件性眨眼反应都可以与结果预期区分开来。
J Exp Psychol Anim Behav Process. 2012 Jan;38(1):1-10. doi: 10.1037/a0024411. Epub 2011 Jul 4.
10
Hippocampal and cerebellar single-unit activity during delay and trace eyeblink conditioning in the rat.大鼠延迟和痕迹眨眼条件反射过程中海马和小脑的单单位活动
Neurobiol Learn Mem. 2007 Feb;87(2):269-84. doi: 10.1016/j.nlm.2006.08.014. Epub 2006 Oct 13.

引用本文的文献

1
Valenced tactile information is evoked by neutral visual cues following emotional learning.在情绪学习后,中性视觉线索会引发有正负效价的触觉信息。
Imaging Neurosci (Camb). 2024 Oct 17;2. doi: 10.1162/imag_a_00320. eCollection 2024.
2
Intra-individual comparison of appetitive trace and delay conditioning in humans across acquisition and extinction.人类在习得和消退过程中食欲性痕迹条件反射与延迟条件反射的个体内比较。
Sci Rep. 2025 Jun 20;15(1):20156. doi: 10.1038/s41598-025-05350-0.
3
Pain anticipation is a new behavioural sign of minimally conscious state.
疼痛预期是微意识状态的一种新的行为迹象。
Brain Commun. 2024 Sep 16;6(5):fcae311. doi: 10.1093/braincomms/fcae311. eCollection 2024.
4
Touching the unconscious in the unconscious - hypnotic communication with unconscious patients.在无意识状态下触碰无意识者——与无意识患者的催眠交流。
Front Psychol. 2024 Jun 20;15:1389449. doi: 10.3389/fpsyg.2024.1389449. eCollection 2024.
5
Differential effects of bilateral hippocampal CA3 damage on the implicit learning and recognition of complex event sequences.双侧海马 CA3 区损伤对复杂事件序列内隐学习和识别的差异影响。
Cogn Neurosci. 2024 Apr;15(2):27-55. doi: 10.1080/17588928.2024.2315818. Epub 2024 Feb 21.
6
Neural indices of multimodal sensory and autonomic hyperexcitability in fibromyalgia.纤维肌痛中多模式感觉和自主神经功能亢进的神经指标
Neurobiol Pain. 2023 Jul 22;14:100140. doi: 10.1016/j.ynpai.2023.100140. eCollection 2023 Aug-Dec.
7
Next frontiers in consciousness research.意识研究的下一个前沿。
Neuron. 2023 Oct 18;111(20):3150-3153. doi: 10.1016/j.neuron.2023.09.042.
8
Information-theoretic analysis of Hierarchical Temporal Memory-Spatial Pooler algorithm with a new upper bound for the standard information bottleneck method.基于标准信息瓶颈方法新上界的分层时间记忆-空间池化算法的信息论分析
Front Comput Neurosci. 2023 Jun 7;17:1140782. doi: 10.3389/fncom.2023.1140782. eCollection 2023.
9
Effects of working memory load and CS-US intervals on delay eyeblink conditioning.工作记忆负荷和条件刺激-非条件刺激间隔对延迟性眨眼条件反射的影响。
NPJ Sci Learn. 2023 May 20;8(1):16. doi: 10.1038/s41539-023-00167-w.
10
The little brain and the seahorse: Cerebellar-hippocampal interactions.小脑与海马体:小脑-海马体相互作用
Front Syst Neurosci. 2023 Mar 23;17:1158492. doi: 10.3389/fnsys.2023.1158492. eCollection 2023.