Veterans Affairs Medical Center, San Diego, CA 92161, United States.
Neurobiol Learn Mem. 2011 Feb;95(2):118-24. doi: 10.1016/j.nlm.2010.12.003. Epub 2010 Dec 9.
Systems consolidation involves a prolonged process of memory reorganization that appears to be distinctly related to declarative memory. Declarative memory can be sharply contrasted with simple delay eyeblink classical conditioning, a prototypical example of nondeclarative memory. Yet inserting a trace interval between the conditioned and unconditioned stimuli endows eyeblink (trace) conditioning with many features of declarative memory. Work in humans has established that trace conditioning requires declarative memory. Recently trace eyeblink conditioning in animals has become one of the most powerful methods to study systems consolidation. Thus, it is ironic that a substantially nondeclarative form of memory has been so instructive concerning the organization of declarative memory.
系统巩固涉及到记忆重组的一个长期过程，这个过程与陈述性记忆明显相关。陈述性记忆可以与简单的延迟眨眼经典条件反射形成鲜明对比，经典条件反射是一种非陈述性记忆的典型例子。然而，在条件刺激和无条件刺激之间插入一个痕迹间隔，使眨眼（痕迹）条件反射具有许多陈述性记忆的特征。人类的研究已经证实，痕迹条件反射需要陈述性记忆。最近，动物的痕迹眨眼条件反射已经成为研究系统巩固的最有力方法之一。因此，具有实质性非陈述性记忆的形式对于陈述性记忆的组织如此有启发性，这是具有讽刺意味的。
