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慢性阻塞性肺疾病(COPD)终末期成人患者的特征。

Characteristics of adults dying with COPD.

作者信息

Meyer Pamela A, Mannino David M, Redd Stephen C, Olson David R

机构信息

Air Pollution and Respiratory Health Branch, Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention, 1600 Clifton Road NE, MS E-17, Atlanta, GA 30333, USA.

出版信息

Chest. 2002 Dec;122(6):2003-8. doi: 10.1378/chest.122.6.2003.

DOI:10.1378/chest.122.6.2003
PMID:12475839
Abstract

STUDY OBJECTIVE

To describe factors associated with COPD deaths in the United States.

DESIGN

Cross-sectional survey.

PARTICIPANTS

A total of 12,803 decedents in the National Mortality Followback Survey, a nationally representative sample of US deaths in 1993.

METHODS

We compared the characteristics of adults > or = 35 years of age who died with COPD (bronchitis, emphysema, chronic airway obstruction) with those dying without COPD listed on their death certificates.

RESULTS

Of the estimated 225,400 adults who died with COPD in 1993, 16.7% had never smoked. People dying with COPD were more likely than those dying without COPD to be current smokers (odds ratio [OR], 6.5; 95% confidence interval [CI], 4.3 to 9.9) or former smokers (OR, 3.7; 95% CI, 2.5 to 5.3), have a history of asthma (OR, 5.0; 95% CI, 3.2 to 7.8), be underweight (OR, 4.5; 95% CI, 2.8 to 7.2), and be of the white race (OR, 3.1; 95% CI, 2.4 to 4.0), after controlling for age group and sex.

CONCLUSIONS

A significant proportion of COPD-related deaths occurs in never-smokers. Factors such as a history of asthma and being underweight are associated with COPD mortality and may provide additional opportunities for intervention.

摘要

研究目的

描述在美国与慢性阻塞性肺疾病(COPD)死亡相关的因素。

设计

横断面调查。

参与者

全国死亡随访调查中的12803名死者,这是1993年美国具有全国代表性的死亡样本。

方法

我们比较了年龄≥35岁且死于慢性阻塞性肺疾病(支气管炎、肺气肿、慢性气道阻塞)的成年人与死亡证明上未列出慢性阻塞性肺疾病的死者的特征。

结果

在1993年估计死于慢性阻塞性肺疾病的225400名成年人中,16.7%从未吸烟。与未患慢性阻塞性肺疾病而死亡的人相比,死于慢性阻塞性肺疾病的人更有可能是当前吸烟者(优势比[OR],6.5;95%置信区间[CI],4.3至9.9)或曾经吸烟者(OR,3.7;95%CI,2.5至5.3),有哮喘病史(OR,5.0;95%CI,3.2至7.8),体重过轻(OR,4.5;95%CI,2.8至7.2),以及是白人(OR,3.1;95%CI,2.4至4.0),在对年龄组和性别进行控制之后。

结论

相当一部分与慢性阻塞性肺疾病相关的死亡发生在从不吸烟者中。哮喘病史和体重过轻等因素与慢性阻塞性肺疾病死亡率相关,可能提供额外的干预机会。

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