Bezza A, El Maghraoui A, Ghadouane M, Tabache F, Abouzahir A, Abbar M, Ghafir D, Ohayon V, Archane M I
Medicine Department B, Mohammed V Military Teaching Hospital Rabat Teaching Hospital, Morocco.
Joint Bone Spine. 2002 Oct;69(5):502-5. doi: 10.1016/s1297-319x(02)00438-4.
The case of a 52-year-old man with retroperitoneal fibrosis and ankylosing spondylitis is described. Inflammatory low back pain and acute renal insufficiency prompted a computed tomography scan of the abdomen with contrast agent injection. A fibrous sheath surrounding the aorta and attracting the ureters toward the midline was seen, strongly suggesting retroperitoneal fibrosis. The diagnosis of ankylosing spondylitis was based on the presence of inflammatory low back pain responsive to nonsteroidal anti-inflammatory drugs, syndesmophytes at the lumbar and cervical spine, bilateral sacroiliitis, and presence of the HLA-B27 antigen. Prednisone therapy in a daily dosage of 1 mg/kg induced a marked improvement. Only nine cases of concomitant retroperitoneal fibrosis and ankylosing spondylitis have been reported. These two conditions share similarities in some of the etiologic factors and anatomic localizations, suggesting that both may stem from a predisposition to fibrotic diseases.
本文描述了一名52岁患有腹膜后纤维化和强直性脊柱炎的男性病例。炎性腰背痛和急性肾功能不全促使进行了腹部计算机断层扫描并注射造影剂。可见围绕主动脉的纤维鞘并将输尿管拉向中线，强烈提示腹膜后纤维化。强直性脊柱炎的诊断基于对非甾体抗炎药有反应的炎性腰背痛、腰椎和颈椎的韧带骨赘、双侧骶髂关节炎以及HLA - B27抗原的存在。每日剂量为1mg/kg的泼尼松治疗带来了显著改善。仅报告了9例合并腹膜后纤维化和强直性脊柱炎的病例。这两种疾病在一些病因和解剖定位上有相似之处，提示两者可能都源于纤维化疾病的易感性。
