与苯妥英治疗相关的可逆性全低丙种球蛋白血症。

Reversible panhypogammaglobulinemia associated with phenytoin treatment.

作者信息

Pereira Luis F, Sanchez Juan F

机构信息

Laboratorio de Inmunologia, Hospital San Pedro de Alcantara, Cáceres, Spain.

出版信息

Scand J Infect Dis. 2002;34(10):785-7. doi: 10.1080/00365540260348662.

DOI:10.1080/00365540260348662

PMID:12477340

Abstract

We report the case of a 24-y-old woman who presented with repeated episodes of otitis due to panhypogammaglobulinemia and low levels of mature CD19 + B cells (84 cells/microl) associated with phenytoin treatment. Lymphocyte subpopulations and immunoglobulin levels need to be monitored if symptoms indicating immunodeficiency occur after the initiation of this treatment.

摘要

我们报告了一例24岁女性病例，该患者因全低丙种球蛋白血症以及与苯妥英治疗相关的成熟CD19 + B细胞水平低（84个细胞/微升）而反复出现中耳炎。如果在开始这种治疗后出现免疫缺陷的症状，则需要监测淋巴细胞亚群和免疫球蛋白水平。