[Contractile myocardial proteins and their enzymatic activity in hypertensive disease and coronary atherosclerosis].

An investigation into the fractional composition of myocardial proteins and ATP-ase activity of myosine in 86 persons, who during their lifetime suffered from hypertensive disease and coronary incompetence, revealed significant changes therein. An increased content of actomyosine complex proteins in hypertensive disease was superseded by their considerable diminution in the event of developing cardiac insufficiency, which was at that accompanied by declining ATP-ase activity of myosine. The development of acute myocardial infarction led to a still drastically reduced concentration of sarcoplasmatic and contractile proteins of the heart muscle, as well as to their diminished enzymatic activity.