Carone Mauro, Donner Claudio F
Division of Respiratory Disease, Salvatore Maugeri Foundation, Scientific Institute of Veruno NO, 28010 Veruno, Italy.
Respir Care Clin N Am. 2002 Sep;8(3):479-90. doi: 10.1016/s1078-5337(02)00028-x.
The interest in measuring HS or QoL in patients with respiratory diseases has increased progressively over the last decade, but only recently has it been applied to patients with more severe disease (ie, patients with CRF who are receiving LTOT or NIPPV). The impact of CRF on the daily life and well being of patients can be measured in a number of different ways. There is evidence, however, that it is not possible to predict patients' health from surrogate measures (eg, spirometry or exercise performance) and that the size of the health gain following treatments or interventions cannot be predicted from changes in physiologic measurements. Adequate assessments of HS can be measured directly only through the use of valid and reliable QoL questionnaires. A range of different instruments is available in the literature. The SGRQ and MRF28 have been shown to be applicable and reliable in patients on long-term ventilation.
在过去十年中，对测量呼吸系统疾病患者的健康状况（HS）或生活质量（QoL）的兴趣逐渐增加，但直到最近才应用于病情更严重的患者（即接受长期氧疗或无创正压通气的慢性呼吸衰竭患者）。慢性呼吸衰竭对患者日常生活和幸福感的影响可以通过多种不同方式进行测量。然而，有证据表明，无法通过替代指标（如肺活量测定或运动表现）来预测患者的健康状况，并且治疗或干预后健康改善的程度也无法根据生理测量值的变化来预测。只有通过使用有效且可靠的生活质量问卷，才能直接测量健康状况的充分评估。文献中有一系列不同的工具。圣乔治呼吸问卷（SGRQ）和医学研究委员会呼吸困难量表28项版本（MRF28）已被证明适用于长期通气的患者且具有可靠性。
