Lipetz J, Boswell R E
Experientia. 1976 Jan 15;32(1):48-50. doi: 10.1007/BF01932617.
Explants from young and old mouse kidneys give rise to two different cell types when placed in organ culture dishes. The two cell types differ in morphology and ability to grow in vitro. Explants from young mice give rise to one predominant cell type; those from old mice give rise to another. Our data supports the mosaic theory of aging.
将幼年和老年小鼠的肾外植体置于器官培养皿中时，会产生两种不同的细胞类型。这两种细胞类型在形态和体外生长能力上有所不同。幼年小鼠的外植体产生一种主要的细胞类型；老年小鼠的外植体则产生另一种。我们的数据支持衰老的镶嵌理论。
