Denes Eric, Amaniou Monique, Rogez Jean-Philippe, Weinbreck Pierre, Merle Louis
Service de Maladies Infectieuses et Tropicales, CHU Dupuytren, 87042 Limoges, France.
Ann Med Interne (Paris). 2002 Oct;153(6):411-3.
Hypothermia is an uncommon side effect of acetaminophen. We report 4 cases of HIV-infected patients who developed hypothermia after intravenous injection of propacetamol (the parenteral formulation of acetaminophen). The mechanism of this hypothermia is unknown. AIDS-induced changes in the metabolism of acetaminophen, could be an explanation. AIDS-associated opportunistic diseases may account for part of the mechanism. These hypothermias occur within 6 hours after the injection, are well tolerated and regress spontaneously.
体温过低是对乙酰氨基酚一种不常见的副作用。我们报告了4例HIV感染患者，他们在静脉注射丙帕他莫（对乙酰氨基酚的肠胃外制剂）后出现了体温过低的情况。这种体温过低的机制尚不清楚。艾滋病引起的对乙酰氨基酚代谢变化可能是一种解释。艾滋病相关的机会性疾病可能是部分机制所在。这些体温过低情况在注射后6小时内出现，耐受性良好且会自行消退。
