Döring G K, Kauka E, Netzer A
Geburtshilfe Frauenheilkd. 1976 Jan;36(1):57-61.
In a total of 4149 prenatal patients there were 849 patients who became pregnant following the cessation of the use of oral contraceptives. Results were compared with pregnancies of a similar series of 1000 patients who never had employed contraceptive steroids. Comparison shows a lower incidence of abortion of 5,6% in the oral contraceptive group, compared with 9,2% among the control group. Results show also a lower incidence of toxemia. The incidence of obstetrical surgery was a little higher than in the control group. The incidence of premature birth, perinatal mortality, congenital anomalies, the frequency of twins and of asphyxia neonatorum were similar in both groups. A special group of 107 pregnancies occurring immediatly after cessation of the pill shows no higher risks in pregnancy, during birth or with regard to fetal outcome. An exception is made by the incidence of premature birth that was in this special group 8,8% compared with 5,4% among the control group.
在总共4149名产前患者中,有849名患者在停止使用口服避孕药后怀孕。将结果与1000名从未使用过避孕类固醇的类似系列患者的妊娠情况进行了比较。比较显示,口服避孕药组的流产发生率为5.6%,而对照组为9.2%。结果还显示子痫前期的发生率较低。产科手术的发生率略高于对照组。两组早产、围产期死亡率、先天性异常、双胞胎频率和新生儿窒息的发生率相似。在停药后立即发生的107例妊娠的特殊组中,妊娠、分娩期间或胎儿结局方面没有更高的风险。早产发生率是个例外,该特殊组的早产发生率为8.8%,而对照组为5.4%。