与甲硝唑治疗相关的可逆性磁共振成像和磁共振波谱异常。
Reversible MR imaging and MR spectroscopy abnormalities in association with metronidazole therapy.
作者信息
Cecil Kim M, Halsted Mark J, Schapiro Mark, Dinopoulos Argirios, Jones Blaise V
机构信息
Department of Radiology/MLC 5031, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
出版信息
J Comput Assist Tomogr. 2002 Nov-Dec;26(6):948-51. doi: 10.1097/00004728-200211000-00016.
We present a report of MRI and proton MR spectroscopy (MRS) findings in an adolescent patient with Down syndrome and Crohn disease treated with metronidazole. MRI revealed signal abnormalities within the corpus callosum, basal ganglia, and brainstem. Proton MRS examination demonstrated a persistent lactate elevation during metronidazole treatment. Clinical, spectroscopic, and imaging abnormalities resolved with discontinuation of metronidazole.
我们报告了一例患有唐氏综合征和克罗恩病的青少年患者在接受甲硝唑治疗时的MRI及质子磁共振波谱（MRS）检查结果。MRI显示胼胝体、基底神经节和脑干内有信号异常。质子MRS检查显示在甲硝唑治疗期间乳酸持续升高。停用甲硝唑后，临床、波谱及影像异常均消失。
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