Naqi Rohana, Azeemuddin Muhammad, Beg Mirza Amanullah
Department of Radiology, The Aga Khan University Hospital, Karachi.
J Pak Med Assoc. 2012 Aug;62(8):843-4.
We describe a case demonstrating Magnetic Resonance (MR) imaging findings in association with Metronidazole (Flagyl) toxicity. MRI brain showed abnormal signal intensity involving dentate nuclei of cerebellum bilaterally symmetrical. The diagnosis of metronidazole toxicity was made by the MR imaging findings and supported clinically. In hospital, course of treatment drug was discontinued. Patient improved clinically with discontinuation of metronidazole. No follow-up MR imaging was obtained. In this report, we present a case depicting MR imaging changes within the dentate nuclei of cerebellum.
我们描述了一例显示磁共振（MR）成像结果与甲硝唑（灭滴灵）毒性相关的病例。脑部MRI显示双侧小脑齿状核出现异常信号强度。甲硝唑毒性的诊断依据MR成像结果作出，并得到临床支持。在医院里，停用了治疗药物。停用甲硝唑后患者临床症状改善。未进行后续的MR成像检查。在本报告中，我们呈现了一例描绘小脑齿状核内MR成像变化的病例。
