Pfäffli Pirkko, Hämeilä Mervi, Kuusimäki Leea, Wirmoila Ritva
Department of Industrial Hygiene and Toxicology, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FIN-00250 Helsinki, Finland.
J Chromatogr A. 2002 Dec 27;982(2):261-6. doi: 10.1016/s0021-9673(02)01590-x.
Maleic anhydride has many uses in industry, but workers' exposure to it is poorly known. Our new method allows airborne maleic anhydride to be determined with a limit of quantification of 1 microg/m3 per 12 1 of air, i.e., the concentration of about 0.01 times the occupational exposure standard (0.4 mg/m3). Air samples are collected in Tenax tubes containing sodium sulfate as a drying agent. Maleic anhydride is eluted with methyl tert.-butyl ether containing 5% acetonitrile and 0.1% acetic anhydride, and determined by capillary gas chromatography with electron-capture detection without interference from generic anhydrides. The tested method suits both long-term and short-term measurements.
马来酸酐在工业中有许多用途，但工人接触它的情况却鲜为人知。我们的新方法能够测定空气中的马来酸酐，其定量限为每12升空气中1微克/立方米，即约为职业接触标准（0.4毫克/立方米）的0.01倍浓度。空气样品收集在装有硫酸钠作为干燥剂的Tenax管中。用含有5%乙腈和0.1%乙酸酐的甲基叔丁基醚洗脱马来酸酐，并用带电子捕获检测的毛细管气相色谱法测定，不受一般酸酐的干扰。该测试方法适用于长期和短期测量。
