De Oliveira T, Miller R, Tarin M, Cassol S
Molecular Virology and Bioinformatics, Africa Centre/University of Natal, Durban, South Africa.
Bioinformatics. 2003 Jan;19(1):153-4. doi: 10.1093/bioinformatics/19.1.153.
Sequence databases encode a wealth of information needed to develop improved vaccination and treatment strategies for the control of HIV and other important pathogens. To facilitate effective utilization of these datasets, we developed a user-friendly GDE-based LINUX interface that reduces input/output file formatting.
GDE was adapted to the Linux operating system, bioinformatics tools were integrated with microbe-specific databases, and up-to-date GDE menus were developed for several clinically important viral, bacterial and parasitic genomes. Each microbial interface was designed for local access and contains Genbank, BLAST-formatted and phylogenetic databases.
GDE-Linux is available for research purposes by direct application to the corresponding author. Application-specific menus and support files can be downloaded from (http://www.bioafrica.net).
序列数据库编码了开发用于控制HIV和其他重要病原体的改进疫苗接种和治疗策略所需的大量信息。为了便于有效利用这些数据集，我们开发了一个基于GDE的用户友好型LINUX界面，该界面减少了输入/输出文件格式设置。
GDE被适配到Linux操作系统，生物信息学工具与特定微生物数据库集成，并为几种临床重要的病毒、细菌和寄生虫基因组开发了最新的GDE菜单。每个微生物界面都设计用于本地访问，并包含Genbank、BLAST格式和系统发育数据库。
GDE-Linux可通过直接向相应作者申请用于研究目的。特定应用的菜单和支持文件可从（http://www.bioafrica.net）下载。
