ModView，多蛋白序列和结构的可视化工具。

ModView, visualization of multiple protein sequences and structures.

作者信息

Ilyin Valentin A, Pieper Ursula, Stuart Ashley C, Marti-Renom Marc A, McMahan Linda, Sali Andrej

机构信息

The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA.

出版信息

Bioinformatics. 2003 Jan;19(1):165-6. doi: 10.1093/bioinformatics/19.1.165.

DOI:10.1093/bioinformatics/19.1.165

PMID:12499313

Abstract

SUMMARY

We describe ModView, a web application for visualization of multiple protein sequences and structures. ModView integrates a multiple structure viewer, a multiple sequence alignment editor, and a database querying engine. It is possible to interactively manipulate hundreds of proteins, to visualize conservative and variable residues, active and binding sites, fragments, and domains in protein families, as well as to display large macromolecular complexes such as ribosomes or viruses. As a Netscape plug-in, ModView can be included in HTML pages along with text and figures, which makes it useful for teaching and presentations. ModView is also suitable as a graphical interface to various databases because it can be controlled through JavaScript commands and called from CGI scripts.

AVAILABILITY

ModView is available at http://guitar.rockefeller.edu/modview.

摘要

我们描述了ModView，一个用于可视化多个蛋白质序列和结构的网络应用程序。ModView集成了一个多结构查看器、一个多序列比对编辑器和一个数据库查询引擎。用户可以交互式地操作数百种蛋白质，可视化保守和可变残基、活性和结合位点、片段以及蛋白质家族中的结构域，还能展示大型大分子复合物，如核糖体或病毒。作为一个Netscape插件，ModView可以与文本和图形一起包含在HTML页面中，这使其在教学和演示中很有用。ModView也适合作为各种数据库的图形界面，因为它可以通过JavaScript命令进行控制，并从CGI脚本调用。