用于比较蛋白质结构建模与分析的工具。
Tools for comparative protein structure modeling and analysis.
作者信息
Eswar Narayanan, John Bino, Mirkovic Nebojsa, Fiser Andras, Ilyin Valentin A, Pieper Ursula, Stuart Ashley C, Marti-Renom Marc A, Madhusudhan M S, Yerkovich Bozidar, Sali Andrej
机构信息
Department of Biopharmaceutical Sciences and California Institute for Quantitative Biomedical Research, University of California, San Francisco, CA 94143-2240, USA.
出版信息
Nucleic Acids Res. 2003 Jul 1;31(13):3375-80. doi: 10.1093/nar/gkg543.
Abstract
The following resources for comparative protein structure modeling and analysis are described (http://salilab.org): MODELLER, a program for comparative modeling by satisfaction of spatial restraints; MODWEB, a web server for automated comparative modeling that relies on PSI-BLAST, IMPALA and MODELLER; MODLOOP, a web server for automated loop modeling that relies on MODELLER; MOULDER, a CPU intensive protocol of MODWEB for building comparative models based on distant known structures; MODBASE, a comprehensive database of annotated comparative models for all sequences detectably related to a known structure; MODVIEW, a Netscape plugin for Linux that integrates viewing of multiple sequences and structures; and SNPWEB, a web server for structure-based prediction of the functional impact of a single amino acid substitution.
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The Protein Data Bank.蛋白质数据库。
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LigBase: a database of families of aligned ligand binding sites in known protein sequences and structures.LigBase：一个关于已知蛋白质序列和结构中对齐配体结合位点家族的数据库。
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