Restivo D A, Lanza S, Patti F, Giuffrida S, Marchese-Ragona R, Bramanti P, Palmeri A
Department of Physiological Sciences, University of Catania, Italy.
Neurology. 2002 Dec 24;59(12):1971-3. doi: 10.1212/01.wnl.0000036911.75478.fa.
Fourteen diabetic subjects with gustatory sweating were treated by intracutaneous injections of botulinum toxin type A into the affected facial skin areas. In all subjects, sweating (measured by Minor starch iodine test) ceased within 4 days, with the maximal follow-up time lasting 24 weeks. This therapeutic approach, which could be used to reduce the severity of diabetic gustatory sweating, appears to be long lasting, adverse effect free, and minimally invasive.
14名患有味觉性多汗症的糖尿病患者接受了在患侧面部皮肤区域皮内注射A型肉毒杆菌毒素的治疗。在所有患者中，出汗（通过Minor淀粉碘试验测量）在4天内停止，最长随访时间为24周。这种可用于减轻糖尿病味觉性多汗症严重程度的治疗方法似乎效果持久、无不良反应且微创。
