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帕金森病中的幻觉与睡眠-觉醒周期:一项24小时连续多导睡眠图研究

Hallucinations and sleep-wake cycle in PD: a 24-hour continuous polysomnographic study.

作者信息

Manni R, Pacchetti C, Terzaghi M, Sartori I, Mancini F, Nappi G

机构信息

Unit of Sleep Medicine, IRCCS C. Mondino Institute of Neurology, Pavia, Italy.

出版信息

Neurology. 2002 Dec 24;59(12):1979-81. doi: 10.1212/01.wnl.0000038351.32678.4a.

DOI:10.1212/01.wnl.0000038351.32678.4a
PMID:12499497
Abstract

Twenty-four-hour ambulatory polysomnography was performed in 20 patients with PD who were having visual hallucinations (12 men and 8 women, mean age 70 +/- 6 years). Visual hallucinations were clearly related to daytime NREM sleep or nocturnal REM sleep in 33% of the instances. The data reinforce the hypothesis that neural mechanisms implicated in generating sleep and, in particular, in dream imagery play a role in the occurrence of visual hallucinations in PD.

摘要

对20名患有视幻觉的帕金森病患者进行了24小时动态多导睡眠监测(其中12名男性,8名女性,平均年龄70±6岁)。在33%的情况下,视幻觉与白天的非快速眼动睡眠或夜间的快速眼动睡眠明显相关。这些数据强化了这样一种假设,即参与产生睡眠,特别是梦境意象的神经机制在帕金森病视幻觉的发生中起作用。

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