Paul Robert H, Cohen Ronald A, Moser David J, Browndyke Jeff N, Davis Kelly, Gordon Norman, Sweet Lawrence, Lawrence Jeffrey J, Zawacki Tricia
Brown Medical School, Providence, RI 20903, USA.
Cerebrovasc Dis. 2003;15(1-2):116-20. doi: 10.1159/000067138.
The Dementia Rating Scale (DRS) is a common measure of cognitive function, but its sensitivity to identify deficits across cognitive domains in vascular dementia (VaD) remains unclear.
We compared the sensitivity and specificity of two recommended cutoff scores of the DRS. Thirty-eight patients diagnosed with VaD participated in the current study.
The original recommendations resulted in poor sensitivity for the DRS total score and attention, construction, and memory subscales. The more recent recommendations greatly improved the sensitivity of the subscales and the total DRS score, but resulted in decreased specificity. Correlations between the specific DRS subscales and criterion measures of cognitive function revealed good convergent and divergent validity for most subscales.
The DRS is a valid measure of cognitive dysfunction in VaD, but clinicians should consider using the more recent recommendations developed for AD to determine impaired performances in VaD.
痴呆评定量表（DRS）是认知功能的常用测量方法，但其识别血管性痴呆（VaD）各认知领域缺陷的敏感性尚不清楚。
我们比较了DRS两个推荐临界值的敏感性和特异性。38名被诊断为VaD的患者参与了本研究。
最初的推荐导致DRS总分以及注意力、结构和记忆分量表的敏感性较差。最新的推荐极大地提高了分量表和DRS总分的敏感性，但特异性降低。特定DRS分量表与认知功能标准测量之间的相关性表明，大多数分量表具有良好的聚合效度和区分效度。
DRS是测量VaD认知功能障碍的有效方法，但临床医生应考虑使用为阿尔茨海默病（AD）制定的最新推荐来确定VaD患者的受损表现。
