Sheikh Salwa S, Massloom Hasan S
Pathology Services Division, Surgical and Diagnostic Services Department, Dhahran Health Center, Saudi Aramco, Dhahran, Saudi Arabia.
ORL J Otorhinolaryngol Relat Spec. 2002 Nov-Dec;64(6):448-50. doi: 10.1159/000067574.
Fat-containing lesions of endocrine organs are rare. Distinguishing lipoadenomas of the thyroid gland from lipoadenomas of parathyroid glands can be challenging during intraoperative consultation. Our patient had a well-circumscribed tan-pink nodule present on the surface of the thyroid gland, exhibiting abundant fat interspersed between the cells, with ample eosinophilic cytoplasm arranged in trabeculae and solid sheets. Immunohistochemistry showed strong positivity for thyroglobulin confirming the origin of the nodule to be thyroid. Only few cases of lipoadenomas of the thyroid and parathyroid have been reported in the literature. There is considerable histologic overlap between the two, making it difficult to determine the site of origin. We briefly discuss the features that may be helpful in this distinction.
内分泌器官的含脂肪病变较为罕见。在术中会诊时，区分甲状腺脂肪瘤和甲状旁腺脂肪瘤具有挑战性。我们的患者甲状腺表面有一个边界清晰的棕褐色至粉红色结节，细胞间可见大量脂肪，有丰富的嗜酸性细胞质，呈小梁状和实性片状排列。免疫组织化学显示甲状腺球蛋白呈强阳性，证实该结节起源于甲状腺。文献中仅报道了少数甲状腺和甲状旁腺脂肪瘤病例。两者在组织学上有相当大的重叠，难以确定起源部位。我们简要讨论可能有助于这种区分的特征。
