既往人工流产史与后续足月妊娠期间物质使用情况的关系。

A history of induced abortion in relation to substance use during subsequent pregnancies carried to term.

作者信息

Coleman Priscilla K, Reardon David C, Rue Vincent M, Cougle Jesse

机构信息

Department of Psychology, University of the South, Sewanee, Tenn, USA.

出版信息

Am J Obstet Gynecol. 2002 Dec;187(6):1673-8. doi: 10.1067/mob.2002.127602.

DOI:10.1067/mob.2002.127602

PMID:12501082

Abstract

OBJECTIVE

Previous research has revealed a general association between induced abortion and substance use. The purpose of this study was to examine the correlation when substance use is measured specifically during a subsequent pregnancy.

STUDY DESIGN

A nationally representative sample of women was surveyed about substance use during pregnancy shortly after giving birth. Women with a previous induced abortion, whose second pregnancy was delivered, were compared separately with women with one previous birth and with women with no previous births.

RESULTS

Compared with women who gave birth, women who had had an induced abortion were significantly more likely to use marijuana (odds ratio, 10.29; 95% CI, 3.47-30.56), various illicit drugs (odds ratio, 5.60; 95% CI, 2.39-13.10), and alcohol (odds ratio, 2.22; 95% CI, 1.31-3.76) during their next pregnancy. The results with only first-time mothers were very similar.

CONCLUSION

Psychosocial mechanisms that may explain the findings are discussed. Screening for abortion history may help to identify pregnant women who are at risk for substance use more effectively.

摘要

目的

先前的研究揭示了人工流产与物质使用之间的普遍关联。本研究的目的是在后续妊娠期间专门测量物质使用情况时，检验两者之间的相关性。

研究设计

对全国具有代表性的女性样本在产后不久进行了关于孕期物质使用情况的调查。将有过一次人工流产且第二次妊娠已分娩的女性，分别与有过一次生育史的女性以及无生育史的女性进行比较。

结果

与已生育的女性相比，有过人工流产史的女性在下一次妊娠期间使用大麻（比值比，10.29；95%可信区间，3.47 - 30.56）、各种非法药物（比值比，5.60；95%可信区间，2.39 - 13.10）和酒精（比值比，2.22；95%可信区间，1.31 - 3.76）的可能性显著更高。仅针对初产妇的结果非常相似。