Ovsiannikov V I, Berezina T P
Institute of Experimental Medicine of the Russian Acad. Med. Sci., St. Petersburg, 197376, Acad. Pavlov St., 12, Russia.
Ross Fiziol Zh Im I M Sechenova. 2002 Aug;88(8):1017-27.
I. v. administration of serotonin to alert rabbits produced a phasic change of contractile activity of duodenum, ileum, and jejunum including excitatory and inhibitory components. It is shown that stimulation of the small bowel motility is caused by serotonin activation of non-cholinergic excitatory mechanism with participation of effector cholinergic neurones. The initial suppression of the motility is caused by participation of nonadrenergic noncholinergic inhibitory mechanism, and the secondary inhibition of contractile activity of a small bowel with serotonin has an adrenergic nature.
静脉注射血清素使警觉的兔子十二指肠、回肠和空肠的收缩活动产生阶段性变化，包括兴奋和抑制成分。结果表明，小肠运动的刺激是由血清素激活非胆碱能兴奋机制并伴有效应胆碱能神经元参与引起的。运动的最初抑制是由非肾上腺素能非胆碱能抑制机制的参与导致的，而血清素引起的小肠收缩活动的继发性抑制具有肾上腺素能性质。
