Rosenoff S H, Young R C, Anderson T, Bagley C, Chabner B, Schein P S, Hubbard S, DeVita V T
Ann Intern Med. 1975 Jul;83(1):37-41. doi: 10.7326/0003-4819-83-1-37.
Peritoneoscopy was done within 1 month of exploratory laparotomy in 30 consecutive patients, with ovarian carcinoma as part of their pretreatment evaluation. Six of the 7 patients who were thought to have ovarian carcinoma localized to the pelvis (stages I and II) were found to have advanced disease (stage III) at peritoneoscopy and thus required a change in therapy. Metastatic diaphragmatic involvement in ovarian carcinoma is common and was found in 77 percent of all patients studied. The routine shielding if the liver area ordinarily used with total abdominal radiotherapy would select these patients for therapeutic failure. Peritoneoscopy supplied reevaluable finding in 2 of 7 patients having normal physical, roentgenologic, and laboratory examinations, as well as in 93 percent of all patients stuided. "Second look" peritoneoscopy precluded the need the laparotomy in 5 to 13 patients achieving as apparent clinical remission.
30例连续患者在剖腹探查术后1个月内接受了腹腔镜检查，作为卵巢癌术前评估的一部分。7例被认为卵巢癌局限于盆腔（I期和II期）的患者中，有6例在腹腔镜检查时被发现患有晚期疾病（III期），因此需要改变治疗方案。卵巢癌转移至膈肌很常见，在所有研究患者中占77%。通常在全腹放疗时对肝脏区域进行常规屏蔽会导致这些患者治疗失败。在7例体格检查、X线检查和实验室检查均正常的患者中，有2例通过腹腔镜检查获得了可重新评估的结果，在所有研究患者中这一比例为93%。对于5至13例达到明显临床缓解的患者，“二次探查”腹腔镜检查避免了剖腹手术的需要。
